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gastroplus tm pbpk simulator program  (Simulations Plus Inc)

 
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    Simulations Plus Inc gastroplus tm pbpk simulator program
    Gastroplus Tm Pbpk Simulator Program, supplied by Simulations Plus Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/gastroplus%C2%AE+program/pmc11434838-298-6-11?v=Simulations+Plus+Inc
    Average 90 stars, based on 1 article reviews
    gastroplus tm pbpk simulator program - by Bioz Stars, 2026-06
    90/100 stars

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    Summary of the Input Parameters Employed for the Gastroplus Simulation

    Journal: The AAPS Journal

    Article Title: Clinical Pharmacokinetics of Buffered Propranolol Sublingual Tablet (Promptol™)—Application of a New “Physiologically Based” Model to Assess Absorption and Disposition

    doi: 10.1208/s12248-013-9479-1

    Figure Lengend Snippet: Summary of the Input Parameters Employed for the Gastroplus Simulation

    Article Snippet: The computational program Gastroplus (version 6.0, Simulations Plus, Inc., Lancaster, CA, USA) was utilized for fitting of the data (see “ Methods ”) with slight modification.

    Techniques: Molecular Weight, Solubility, Formulation, Drug discovery, Diffusion-based Assay, Clinical Proteomics, Concentration Assay, Extraction

    The % absorption of propranolol in human tissue simulated using GastroPlus following sublingual administration of (a) 10 mg Promptol™, (b) 40 mg Inderal®, (c) 40 mg Promptol™, and (d) oral administration of 10 mg Inderal®. The open square boxes are the observed Cp-prop data (mean ± SD)

    Journal: The AAPS Journal

    Article Title: Clinical Pharmacokinetics of Buffered Propranolol Sublingual Tablet (Promptol™)—Application of a New “Physiologically Based” Model to Assess Absorption and Disposition

    doi: 10.1208/s12248-013-9479-1

    Figure Lengend Snippet: The % absorption of propranolol in human tissue simulated using GastroPlus following sublingual administration of (a) 10 mg Promptol™, (b) 40 mg Inderal®, (c) 40 mg Promptol™, and (d) oral administration of 10 mg Inderal®. The open square boxes are the observed Cp-prop data (mean ± SD)

    Article Snippet: The computational program Gastroplus (version 6.0, Simulations Plus, Inc., Lancaster, CA, USA) was utilized for fitting of the data (see “ Methods ”) with slight modification.

    Techniques: